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Naturopathic Management of Chronic Lyme Disease
by Dr. Bryan J. Rade

Dr. Bryan Rade, ND

What is Chronic Lyme Disease?
Chronic Lyme is an infectious disease initiated by the bacterium Borrelia burgdorferi.  It is associated with a vast milieu of symptoms (indeed, it is known as the great mimicker and can present with symptom pictures similar to chronic fatigue syndrome, fibromyalgia, multiple sclerosis, etc.).  Most commonly its symptoms include:
-          Fatigue
-          Pain (joints, muscles, etc.)
-          Neurological symptoms (numbness, tingling, spasms, etc.)
-          Cognitive symptoms (“brain fog”, loss of memory, anxiety, depression, etc.)
-          Cyclical symptoms (periods of symptom improvement and worsening)
…however this is by no means a comprehensive list, and every chronic Lyme patient is unique.
What about the co-infections?
Lyme is also frequently associated with so-called co-infections; other microorganisms can infect the patient at the same time as Lyme (i.e. transmitted by the same mosquito, fly, or tick) or can infect the host while it is immunocompromised by the Lyme.  The co-infections can include Babesia, Erlichia, and/or Bartonella.
For some patients, the co-infection(s) may indeed be the ONLY infection(s) (i.e. Lyme may actually be cleared from the system, or never present at all – this can account for why we see so many false negatives in Lyme testing) – this is impossible to definitively determine clinically because the co-infection microbes can present with identical symptoms to Lyme (which are non-specific to begin with).  Generally, though, the co-infections can have some specific attributes:
-          Babesia: cherry angiomas (red dots) on the abdomen, issues with breathing (inability to take a deep breath or “air hunger”)
-          Bartonella: red streaks on the abdomen (like scratches), enlarged lymph nodes in the neck
-          Erlichia: not associated with specific attributes distinct from Lyme; sometimes presents with sharp, knife-like pain behind eyes
Are there definitive tests available?
No. Unfortunately the tests that do exist have an abysmally high false negative rate (i.e. they frequently say no infection is present when indeed there is one present).  The sensitivity of comprehensive testing is estimated at 40%.  To test for co-infections, separate tests need to be conducted for them.  The average cost of a comprehensive lab panel with the highly reputable lab IgeneX is approximately $1000 USD.  Statistically speaking, several of these would need to be run in order to definitively rule out Lyme in the face of a negative result (conversely, if one is “lucky” enough to get a positive result then that can be used to base treatment on).
In the absence of a positive lab result, what can we do?
We start with a “therapeutic trial”, meaning that we start treatment as if the patient has Lyme (and/or a co-infection, if symptoms suggest it) and see if their symptoms improve or change in a way that suggests we have the right diagnosis.  Indeed, this method typically shows us results one way or the other within about one months’ time (i.e. if the patient feels better it strongly suggests Lyme; if they feel no change it’s less likely to be Lyme) and is significantly less expensive than running the independent lab tests.
Are there any non-laboratory tests that can give diagnostic information?
Yes.  Specialized testing like Autonomic Response Testing as developed by Dr. Dietrich Klinghardt, MD (one of the world’s leading Lyme experts) can give diagnostic direction, as can related testing methods like applied kinesiology and Koren Specific Technique.
What are the treatment options?
It depends on who you talk to.  Lyme-literate medical doctors typically rely on antibiotic therapy as their primary method of treatment – this can be a combination of oral and intravenous administration.  These MDs get many fantastic results with their patients and have fully resolved many, many cases.  The antibiotic approach is oftentimes associated with periods of “die off” reactions which can lead to unpleasant symptoms, and treatment can sometimes take a long time (several months to a few years, on average).
Lyme-literate integrative doctors (either medical doctors or naturopathic doctors) take a somewhat different approach.  Ideally they like to see patients taking antibiotic therapy (assuming that antibiotics are a good therapeutic tool for the patient) while being supported with other anti-Lyme treatments and treatments to support the patient during the Lyme-killing process.  In doing so, patients are able to resolve the infection(s) faster, feel better sooner, and reduce the “die off” symptoms as much as possible.
Unfortunately, in some situations antibiotics are not an option (e.g. in Nova Scotia if there is no prescribing medical doctor then a treating naturopathic doctor cannot get access to antibiotics) and thus a non-antibiotic approach is the only option.  Indeed, this is virtually always the case for my Lyme patients and me; however we are still able to improve and eventually fully resolve symptoms without antibiotics (although, once again, we would rather have the antibiotics, too, if possible).
What are the naturopathic/integrative medical treatment options?
There are many.  The treatments that I have found to be most effective with my patients include:
-          IV therapy: combination of hydrogen peroxide (kills Lyme and co-infections) and nutrients (B vitamins, magnesium, etc. – to improve energy levels, pain, brain fog, etc.)
-          Anti-Lyme herbs: specific herbs have bacterial killing effects and boost the immune system to seek out and kill Lyme more effectively.  My favourite is Quintessence by BioPure, as recommended by Dr. Klinghardt; additional herbal compounds like artemesinin (for Babesia) and essential oil combinations (rizols) have a powerful synergistic effect against Lyme
-          Immune system enhancement/“waking it up”: Lyme has devised many ways to evade the immune system while still wreaking havoc on the body.  Herbs can help in the regard, but more advanced treatments are often required to really “wake up” the immune system and get it properly patrolling the whole body.  Two advanced treatments include:
o   Autonosode therapy: a simple, in-office procedure that vastly improves the ability of the immune system to scour the body’s connective tissues and nervous system for Lyme (places it frequently hides to evade the immune system)
o   Sinus/Tonsil Neural and Ozone therapy: in-office treatment of these areas with procaine and ozone strongly enhances overall immune system function and directly kills Lyme in two of its main reservoirs in the body (i.e. the sinuses and tonsils)
-          CCSVI (Chronic Cerebrospinal Venous Insufficiency) Protocol: can be done along with sinus/tonsil treatment to enhance blood flow to the brain (in a similar manner to how the Zamboni treatment helps patients with MS) – done as a treatment with procaine and ozone in-office
-          Adrenal Gland Support: our adrenal glands control our energy levels and get depleted in the face of stress.  Chronic Lyme is incredibly stressful on the body and thus the adrenals are virtually always depleted in these patients.  Support with strong doses of herbs and adrenal gland extracts help improve energy levels and mental function quickly.
-          Reducing EMF exposure: EMFs (electromagnetic fields) can significantly aggravate symptoms of Lyme, especially issues with brain fog and insomnia.  Reducing exposure during sleep is crucial to improve recovery time.
-          Dealing with other issues as they arise: in my experience, patients who are actively killing Lyme begin to have other issues arise.  Sometimes they start actively clearing heavy metals (indicated by developing headaches, a metallic taste in the mouth, aggravation by strong scents/chemicals, etc.) or clearing past emotional issues.  Sometimes old symptoms from years before come to the surface again.  As these issues arise they must be dealt with to help the Lyme to be cleared as efficiently as possible.
-          Other therapies: many other therapies can potentially be useful in anti-Lyme protocols, including bee venom therapy, homeopathy, treatments to boost natural killer cells, etc.  Ideally individualized testing is done using autonomic response testing or a similar technique to determine the ideal treatment protocol.
What is the take-home message?
Chronic Lyme is an incredibly challenging issue, made even more challenging by its lack of recognition in the conventional medical community.  Fortunately there are many concerned doctors who are willing to treat what they see, not just what a lab test tells them.  A great deal of support is available to patients who are suffering from chronic Lyme – we’re all working together to spread information and ultimately help people get well.  To the well-trained clinical eye chronic Lyme disease (and its co-infections) is an identifiable condition even in the absence of a positive laboratory result.  From there, effective and comprehensive treatment options are available. 

Dr. Bryan J. Rade, ND
Naturopathic Doctor

Lower Sackville Wellness Centre
546 Sackville Drive
Lower Sackville NS B4C 2S2
P: (902) 830-4615
F: (902) 252-3081

Please view link and visit his website at:

*** Dr. Rade is also giving a thorough discussion on Chronic Lyme disease at the Lower Sackville Wellness Center ~ 546 Sackville Dr., Lower Sackville, Nova Scotia on Tues, March 13, 2012 @ 6:30 pm.
To register Please phone Dr. Rades Reception desk @ (902) 830-4615 ***

Top 100 Stories of 2011 #90: Chronic Lyme Patients Validated?
A new study uncovered biomarkers for Lyme disease symptoms that persist even after treatment.
by Katie Palmer From the January-February special is
sue; published online January 5, 2012

Patients with chronic fatigue syndrome and post-treatment Lyme disease syndrome (in which symptoms persist after antibiotic treatment) have spent decades fending off charges that their debilitating exhaustion and cognitive problems were simply imagined. But a study released last February provides tangible evidence that their conditions are real and distinct entities.
Immunologist Steven Schutzer of the University of Medicine and Dentistry of New Jersey examined samples of cerebrospinal fluid, the clear liquid ?that surrounds the brain and spinal cord, from patients with each syndrome. In identifying the contents of that fluid, he documented different sets of proteins for each group of patients, potential biomarkers that distinguish between the two ?conditions and healthy controls. Schutzer revealed the marker proteins by removing common, unrelated proteins like albumin and immunoglobulin from the spinal fluid before his analysis. “That lets the smaller proteins—the potential biomarkers—not get obscured,” he says. “At least now we know we’re not just speculating about the differences between chronic fatigue syndrome and post-treatment Lyme.”